• The Bible is not even internally consistent, ergo is not perfect, ergo is not the inerrant Word of God, which is what many believe while many more just kind of play along.
• The Bible is full of awful ideas, moral concepts that are inapplicable to modern life, and some that are unacceptable.
• The modern Christian derides a "pick-and-choose" method, but this is inevitable because the teachings of the Bible are mostly impracticable or inapplicable. Modern Christians routinely disregard some arcane laws and accept others as self-evident.
• The teachings as practiced are antithetical to complex human behavior - finding only harm in important natural behaviors while justifying such horror as patriotic wars. Many Christians have protested unjust wars; but many Christian churches have been active supporters, with the Bible as their inspiration.
• People's logic & text-comprehension abilities are distorted by compulsory belief in the holy books. When you have to believe claims that are not true, it causes confusion. This dissonance affects the wider culture and public policy.